These constitute a good selection of papers to introduce one to the lab and the general field of bioinformatics.
One might start with Luscombe et al. (2002) for an introduction to bioinformatics.
Specific fields are highlighted in other short papers:
- Data integration for function prediction
- Gerstein et al. (2002), Bertone and Gerstein (2001), Greenbaum et al. (2001)
- Simulation on molecular structure
- Gerstein and Levitt (1998); Gerstein and Chothia (1999)
- Pseudogenes and genome annotation
- Gerstein and Snyder (2003); Harrison and Gerstein (2002)
- Structural genomics
- Gerstein (2000); Teichmann et al. (1999)
- E-publishing
- Gerstein (1999)
- Expression analysis
- Gerstein and Jansen (2000)
Unfortunately, none of these papers give one much detail on the mathematical or computational aspects of the work. For this, it's best to look at some samples of recent research, which are listed below, to get a sense of the type of mining that we are doing -- e.g. Yu & Gerstein (2006), Du et al. (2006), Lu et al., (2005), Yip et al., (2007), and Echols et al. (2003).
MB Gerstein, A Kundaje, M Hariharan, SG Landt, KK Yan, C Cheng, XJ Mu, E Khurana, J Rozowsky, R Alexander, R Min, P Alves, A Abyzov, N Addleman, N Bhardwaj, AP Boyle, P Cayting, A Charos, DZ Chen, Y Cheng, D Clarke, C Eastman, G Euskirchen, S Frietze, Y Fu, J Gertz, F Grubert, A Harmanci, P Jain, M Kasowski, P Lacroute, JJ Leng, J Lian, H Monahan, H O'Geen, Z Ouyang, EC Partridge, D Patacsil, F Pauli, D Raha, L Ramirez, TE Reddy, B Reed, M Shi, T Slifer, J Wang, L Wu, X Yang, KY Yip, G Zilberman-Schapira, S Batzoglou, A Sidow, PJ Farnham, RM Myers, SM Weissman, M Snyder (2012). Nature 489: 91-100.
DG MacArthur, S Balasubramanian, A Frankish, N Huang, J Morris, K Walter, L Jostins, L Habegger, JK Pickrell, SB Montgomery, CA Albers, ZD Zhang, DF Conrad, G Lunter, H Zheng, Q Ayub, MA DePristo, E Banks, M Hu, RE Handsaker, JA Rosenfeld, M Fromer, M Jin, XJ Mu, E Khurana, K Ye, M Kay, GI Saunders, MM Suner, T Hunt, IH Barnes, C Amid, DR Carvalho-Silva, AH Bignell, C Snow, B Yngvadottir, S Bumpstead, DN Cooper, Y Xue, IG Romero, 1000 Genomes Project Consortium, J Wang, Y Li, RA Gibbs, SA McCarroll, ET Dermitzakis, JK Pritchard, JC Barrett, J Harrow, ME Hurles, MB Gerstein, C Tyler-Smith (2012). Science 335: 823-8.
D Clarke, N Bhardwaj, MB Gerstein (2012). J Struct Biol 179: 320-6.
J Rozowsky, A Abyzov, J Wang, P Alves, D Raha, A Harmanci, J Leng, R Bjornson, Y Kong, N Kitabayashi, N Bhardwaj, M Rubin, M Snyder, M Gerstein (2011). Mol Syst Biol 7: 522.
XJ Mu, ZJ Lu, Y Kong, HY Lam, MB Gerstein (2011). Nucleic Acids Res 39: 7058-76.
S Balasubramanian, L Habegger, A Frankish, DG MacArthur, R Harte, C Tyler-Smith, J Harrow, M Gerstein (2011). Genes Dev 25: 1-10.
G Fang, N Bhardwaj, R Robilotto, MB Gerstein (2010). PLoS Comput Biol 6: e1000703.
A Abyzov, R Bjornson, M Felipe, M Gerstein (2010). Proteins 78: 309-24.
RP Alexander, PM Kim, T Emonet, MB Gerstein (2009). Sci Signal 2: pe44.
C Cheng, LM Li, P Alves, M Gerstein (2009). BMC Genomics 10: 225.
S Balasubramanian, D Zheng, YJ Liu, G Fang, A Frankish, N Carriero, R Robilotto, P Cayting, M Gerstein (2009). Genome Biol 10: R2.
J Rozowsky, G Euskirchen, RK Auerbach, ZD Zhang, T Gibson, R Bjornson, N Carriero, M Snyder, MB Gerstein (2009). Nat Biotechnol 27: 66-75.
HY Lam, E Khurana, G Fang, P Cayting, N Carriero, KH Cheung, MB Gerstein (2009). Nucleic Acids Res 37: D738-43.
R Sasidharan, M Gerstein (2008). Nature 453: 729-31.
J Du, JS Rozowsky, JO Korbel, ZD Zhang, TE Royce, MH Schultz, M Snyder, M Gerstein (2006). Bioinformatics 22: 3016-24.
KY Yip, H Yu, PM Kim, M Schultz, M Gerstein (2006). Bioinformatics 22: 2968-70.
D Zheng, MB Gerstein (2006). Genome Biol 7 Suppl 1: S131-10.
LJ Lu, Y Xia, A Paccanaro, H Yu, M Gerstein (2005). Genome Res 15: 945-53.
R Jansen, H Yu, D Greenbaum, Y Kluger, NJ Krogan, S Chung, A Emili, M Snyder, JF Greenblatt, M Gerstein (2003). Science 302: 449-53.
M Snyder, M Gerstein (2003). Science 300: 258-60.
N Echols, D Milburn, M Gerstein (2003). Nucleic Acids Res 31: 478-82.
PM Harrison, M Gerstein (2002). J Mol Biol 318: 1155-74.
M Gerstein, N Lan, R Jansen (2002). Science 295: 284-7.
NM Luscombe, D Greenbaum, M Gerstein (2001). Methods Inf Med 40: 346-58.
D Greenbaum, NM Luscombe, R Jansen, J Qian, M Gerstein (2001). Genome Res 11: 1463-8.
P Bertone, M Gerstein (2001). IEEE Eng Med Biol Mag 20: 33-40.
M Gerstein (2000). Nat Struct Biol 7 Suppl: 960-3.
M Gerstein, R Jansen (2000). Curr Opin Struct Biol 10: 574-84.
M Gerstein, C Chothia (1999). Science 285: 1682-3.
M Gerstein (1999). Bioinformatics 15: 429-31.
SA Teichmann, C Chothia, M Gerstein (1999). Curr Opin Struct Biol 9: 390-9.
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