Structural Genomics [strgen]
- Robotic cloning and Protein Production Platform of the Northeast Structural Genomics Consortium.
- TB Acton, KC Gunsalus, R Xiao, LC Ma, J Aramini, MC Baran, YW Chiang, T Climent, B Cooper, NG Denissova, SM Douglas, JK Everett, CK Ho, D Macapagal, PK Rajan, R Shastry, LY Shih, GV Swapna, M Wilson, M Wu, M Gerstein, M Inouye, JF Hunt, GT Montelione (2005) Methods Enzymol 394: 210-43.
- Computational analysis of membrane proteins: genomic occurrence, structure prediction and helix interactions.
- U Lehnert, Y Xia, TE Royce, CS Goh, Y Liu, A Senes, H Yu, ZL Zhang, DM Engelman, M Gerstein (2004) Q Rev Biophys 37: 121-46.
- The protein target list of the Northeast Structural Genomics Consortium.
- Z Wunderlich, TB Acton, J Liu, G Kornhaber, J Everett, P Carter, N Lan, N Echols, M Gerstein, B Rost, GT Montelione (2004) Proteins 56: 181-7.
- A method using active-site sequence conservation to find functional shifts in protein families: application to the enzymes of central metabolism, leading to the identification of an anomalous isocitrate dehydrogenase in pathogens.
- R Das, M Gerstein (2004) Proteins 55: 455-63.
- Transmembrane protein domains rarely use covalent domain recombination as an evolutionary mechanism.
- Y Liu, M Gerstein, DM Engelman (2004) Proc Natl Acad Sci U S A 101: 3495-7.
- Mining the structural genomics pipeline: identification of protein properties that affect high-throughput experimental analysis.
- CS Goh, N Lan, SM Douglas, B Wu, N Echols, A Smith, D Milburn, GT Montelione, H Zhao, M Gerstein (2004) J Mol Biol 336: 115-30.
- Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures.
- V Alexandrov, M Gerstein (2004) BMC Bioinformatics 5: 2.
- Data mining crystallization databases: knowledge-based approaches to optimize protein crystal screens.
- MS Kimber, F Vallee, S Houston, A Necakov, T Skarina, E Evdokimova, S Beasley, D Christendat, A Savchenko, CH Arrowsmith, M Vedadi, M Gerstein, AM Edwards (2003) Proteins 51: 562-8.
- SPINE 2: a system for collaborative structural proteomics within a federated database framework.
- CS Goh, N Lan, N Echols, SM Douglas, D Milburn, P Bertone, R Xiao, LC Ma, D Zheng, Z Wunderlich, T Acton, GT Montelione, M Gerstein (2003) Nucleic Acids Res 31: 2833-8.
- Structural genomics: current progress.
- M Gerstein, A Edwards, CH Arrowsmith, GT Montelione (2003) Science 299: 1663.
- Strategies for structural proteomics of prokaryotes: Quantifying the advantages of studying orthologous proteins and of using both NMR and X-ray crystallography approaches.
- A Savchenko, A Yee, A Khachatryan, T Skarina, E Evdokimova, M Pavlova, A Semesi, J Northey, S Beasley, N Lan, R Das, M Gerstein, CH Arrowmith, AM Edwards (2003) Proteins 50: 392-9.
- Structural genomics analysis: characteristics of atypical, common, and horizontally transferred folds.
- H Hegyi, J Lin, D Greenbaum, M Gerstein (2002) Proteins 47: 126-41.
- Genomic analysis of membrane protein families: abundance and conserved motifs.
- Y Liu, DM Engelman, M Gerstein (2002) Genome Biol 3: research0054.
- The dominance of the population by a selected few: power-law behaviour applies to a wide variety of genomic properties.
- NM Luscombe, J Qian, Z Zhang, T Johnson, M Gerstein (2002) Genome Biol 3: RESEARCH0040.
- Structural genomics: a new era for pharmaceutical research.
- Y Liu, NM Luscombe, V Alexandrov, P Bertone, P Harrison, Z Zhang, M Gerstein (2002) Genome Biol 3: REPORTS4004.
- Protein family and fold occurrence in genomes: power-law behaviour and evolutionary model.
- J Qian, NM Luscombe, M Gerstein (2001) J Mol Biol 313: 673-81.
- Global perspectives on proteins: comparing genomes in terms of folds, pathways and beyond.
- R Das, J Junker, D Greenbaum, MB Gerstein (2001) Pharmacogenomics J 1: 115-25.
- SPINE: an integrated tracking database and data mining approach for identifying feasible targets in high-throughput structural proteomics.
- P Bertone, Y Kluger, N Lan, D Zheng, D Christendat, A Yee, AM Edwards, CH Arrowsmith, GT Montelione, M Gerstein (2001) Nucleic Acids Res 29: 2884-98.
- Integrative database analysis in structural genomics.
- M Gerstein (2000) Nat Struct Biol 7 Suppl: 960-3.
- Structural proteomics of an archaeon.
- D Christendat, A Yee, A Dharamsi, Y Kluger, A Savchenko, JR Cort, V Booth, CD Mackereth, V Saridakis, I Ekiel, G Kozlov, KL Maxwell, N Wu, LP McIntosh, K Gehring, MA Kennedy, AR Davidson, EF Pai, M Gerstein, AM Edwards, CH Arrowsmith (2000) Nat Struct Biol 7: 903-9.
- Advances in structural genomics.
- SA Teichmann, C Chothia, M Gerstein (1999) Curr Opin Struct Biol 9: 390-9.
- The relationship between protein structure and function: a comprehensive survey with application to the yeast genome.
- H Hegyi, M Gerstein (1999) J Mol Biol 288: 147-64.
- Comparing genomes in terms of protein structure: surveys of a finite parts list.
- M Gerstein, H Hegyi (1998) FEMS Microbiol Rev 22: 277-304.
- Patterns of protein-fold usage in eight microbial genomes: a comprehensive structural census.
- M Gerstein (1998) Proteins 33: 518-34.
Return to front page
