Proton sensitivity of ASIC1 appeared with the rise of fishes by changes of residues in the region that follows TM1 in the ectodomain of the channel.

ASIC1
Proton sensitivity of ASIC1 appeared with the rise of fishes by changes of residues in the region that follows TM1 in the ectodomain of the channel.

T Coric, D Zheng, M Gerstein, CM Canessa (2005) J Physiol 568: 725-35.

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