Greenbaum et al - Figure 4 7% 11% 6% 4% 4% 17% 33% 10% 15% 26% 22% 3% 1% 5% 34% 1%8% 10% 2% 8% 3% 22% 28% 20% 23% 11% 5% 2% 5% 32% 3% 19% 23% 18% 2% 1% 7% 36% 1% 12% Metabolism (1) Energy (2) Cell growth, cell division and DNA synthesis (3) Transcription (4) Protein synthesis (5) Cellular organization (30) Unclassified (98, 99) Other c 22.7% 15.2% 12.0% 32.3% 17.8% 70.7% 6.6% 4.7% 10.8%7.2% 65.5% 2.7% 11.5% 6.2% 14.2% 88.8% 0.3% 2.6% 2.1% 6.2% 84.8% 0.3% 5.3% 4.0% 5.7% b Function Cytoplasm Membrane Mitochondria Nucleus Other Localization Secondary structure a 16.4% 45.8% 37.8% 38.2% 16.8% 45.0% 34.1% 19.1% 46.9% 35.0% 17.9% 47.2% 33.5% 17.4% 49.0% a -helix b -sheet Coil